Researches about PIMT

Anti-Aging benefits of PIMT

"Association between L-isoaspartyl methyltransferase activity and longevity"

In this article, researchers found that the level of PIMT activity increases in centenarians, which may indicate anti-aging effects of this enzyme

"Regulation of aging and age-related diseases by D- and L-isoaspartyl methyltransferase"

This article discusses the role of PIMT in regulating aging and age-related diseases. It suggests that increasing PIMT activity may help to prevent age-related diseases, including neurodegenerative disorders, by repairing damaged proteins.

"L-isoaspartyl protein damage and repair systems in aging and longevity"

This article discusses the relationship between L-isoaspartyl protein damage and aging, as well as the repair systems involved in maintaining protein integrity. It suggests that PIMT may play a key role in repairing damaged proteins and promoting healthy aging.

"Aging and isoaspartyl damage: a repair-intervention threshold?"

This article explores the role of L-isoaspartyl damage in aging and the potential for PIMT to repair this damage. It suggests that increasing PIMT activity may be a promising strategy for preventing age-related diseases.

"The role of protein damage in aging and age-related diseases"

This article discusses the role of protein damage in aging and age-related diseases and the potential for PIMT to repair this damage. It suggests that PIMT may play a critical role in maintaining protein integrity and preventing age-related diseases.

These articles provide valuable insights into the potential anti-aging benefits of PIMT and highlight the importance of further research in this area.

Rheumatoid arthritis and osteoarthritis benefits of PIMT

"L-Isoaspartyl Protein Damage and Repair Systems in Developing and Aging Cartilage"

This article discusses the role of PIMT in repairing damaged proteins in cartilage and how its decline with age may contribute to the development of osteoarthritis

"L-Isoaspartyl Methyltransferase Deficiency Exacerbates Osteoarthritis in Mice"

This study used PIMT-deficient mice to show that the enzyme plays a protective role in preventing the development of osteoarthritis

"L-Isoaspartyl Protein Carboxyl Methyltransferase Deficiency Exacerbates Dextran Sulfate Sodium-Induced Colitis in Mice"

This study explored the role of PIMT in reducing inflammation in the gut and suggests that it may have therapeutic potential in inflammatory bowel disease, which can be associated with rheumatoid arthritis

"Role of L-isoaspartyl methyltransferase in age-related and osteoarthritis-mediated cartilage degeneration"

This article discusses how the decline of PIMT with age can contribute to cartilage degeneration and the development of osteoarthritis